課程資訊
課程名稱
高等化學生物學專論一
DISCUSSION IN ADVANCED CHEMICAL BIOLOGY(Ⅰ) 
開課學期
99-1 
授課對象
生命科學院  生化科學研究所  
授課教師
陳 平 
課號
Chem8037 
課程識別碼
223ED1660 
班次
 
學分
全/半年
半年 
必/選修
選修 
上課時間
星期一5,6(12:20~14:10)星期四5,6(12:20~14:10) 
上課地點
 
備註
本課程以英語授課。本課程以英語授課。上課教室:化217教室。本課程同為CBMB-TIGP中MB組必修-基礎化學生物及生物物理學。
限博士班
總人數上限:20人 
 
課程簡介影片
 
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課程概述

1. Proteins
2. Nucleic Acids
3. Enzyme Catalysis
4. Carbohydrates
5. Lipids and Membranes
6. Characterization of biomolecules
7. Separation and identification methods, including chromatography and electrophoresis
8. Hydrodynamic methods, including density and molecular volume, ultracentrifugation, sedimentation, diffusion and Brownian motion, and dynamic light scattering
9. Thermodynamics and kinetics methods, including calorimetry, dialysis, protein solubility and crystallization, relaxation, enzyme kinetics, and surface plasma resonance
10. Spectroscopic methods, including UV-Vis spectroscopy, circular dichroism, fluorescence, vibrational spectroscopy (IR and Raman), and NMR spectroscopy
11. Mass spectrometric methods, including ion sources, ionization, mass analyzers, detection, and application
12. Single molecule methods

p.s. The students in this course will be grouped into several teams. In principle, a team will consist of 3–6 students from different disciplines to work together. Each team will be assigned a small project to finish before oral presentation; that is, each team must submit a written report (3 hard copies) and a powerpoint electronic file for oral presentation to Professor Fang by December X. The written report must include description of each slide presented in the powerpoint file. All these materials will be posted on the course website. Only one student in each team will be drawn on site as the team representative to give oral presentation
 

課程目標
1. Proteins
2. Nucleic Acids
3. Enzyme Catalysis
4. Carbohydrates
5. Lipids and Membranes
6. Characterization of biomolecules
7. Separation and identification methods, including chromatography and electrophoresis
8. Hydrodynamic methods, including density and molecular volume, ultracentrifugation, sedimentation, diffusion and Brownian motion, and dynamic light scattering
9. Thermodynamics and kinetics methods, including calorimetry, dialysis, protein solubility and crystallization, relaxation, enzyme kinetics, and surface plasma resonance
10. Spectroscopic methods, including UV-Vis spectroscopy, circular dichroism, fluorescence, vibrational spectroscopy (IR and Raman), and NMR spectroscopy
11. Mass spectrometric methods, including ion sources, ionization, mass analyzers, detection, and application
12. Single molecule methods

p.s. The students in this course will be grouped into several teams. In principle, a team will consist of 3–6 students from different disciplines to work together. Each team will be assigned a small project to finish before oral presentation; that is, each team must submit a written report (3 hard copies) and a powerpoint electronic file for oral presentation to Professor Fang by December X. The written report must include description of each slide presented in the powerpoint file. All these materials will be posted on the course website. Only one student in each team will be drawn on site as the team representative to give oral presentation
 
課程要求
 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
 
參考書目
“Biochemistry” Sixth Edition, by Jeremy M. Berg, John L. Tymoczko, and Lubert
Stryer, W. H. Freeman and Company, NewYork, New York, 2006.

“Principles of Physical Biochemistry” Second Edition, by Kensal E. van Holde,
Curtis Johnson, and Pui Shing Ho, Pearson Education International, 2006. 
評量方式
(僅供參考)
   
課程進度
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日期
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